Mass Spectrometry
and Proteomics

Denis Faubert

Director

 

Team:
- Marguerite Boulos, Research Assistant
- Josée Champagne, Research Assistant
- Sylvain Tessier, Research Assistant

Our platform offers state-of-the-art mass spectrometry services for the identification, characterization and quantification of proteins and small molecules. The analysis of affinity purified protein complexes and post-translational modifications (PTMs) are particularly in demand.

Services

Protein identification 

(In-solution digestion and LC-MS/MS analysis, On-Beads digestion and LC-MS/MS analysis, In-gel digestion and LC-MS/MS analysis, LASER-captured cell proteomics)


Quantitative proteomics

(Label-free, Targeted quantitative analysis (SRM/PRM), SILAC (Stable Isotope labeling with Amino acids in Cell culture), iTRAQ/TMT, Top-down analysis of small proteins (< 30 kDa))


Identification of post-translational modifications

(Phosphoproteomics, Protein characterization)


Small molecule analysis

(Accurate mass measurement of synthetic small molecules, Metabolomics analysis) 


Data analysis and interpretation

Instrumentation

Orbitrap Fusion


Q Exactive
 LTQ Orbitrap Velos
 HPLC-UV (diode array) 
Clean room

 

Guideline for sample
preparation and protocols

Contact the
Mass Spectrometry and
Proteomics services

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