Immunity and Viral Infections

Molecular Immunology

Under the direction of Hua Gu

Research Unit

Intracellular signalling plays an essential role in immune system development and function. Members of the Molecular Immunology Research Unit are interested in how the intracellular signalling molecules communicate with each other and co-ordinately determine T and B lymphocyte development and function.

Using the powerful conditional gene targeting technology, the laboratory has generated various mouse models and used these models to dissect the regulatory mechanisms by which various intracellular signalling networks control the development and function of hematopoietic stem/progenitor cells, lymphocytes, dendritic cells (DCs) under physiological and pathological conditions.

Hua Gu

Research Unit Director

  • Director, Molecular Immunology Research Unit, IRCM
  • Full IRCM Research Professor
  • Full Research Professor, Department of Microbiology, Infectiology and Immunology (accreditation in biomedical science), Université de Montréal
  • Adjunct Professor, Department of Medicine (Division of Experimental Medicine), McGill University
  • Holder of the André-Aisenstadt Chair of Excellence
  • Research Scholar from the Leaders Opportunity Fund, Canada Foundation for Innovation

Degrees and relevant experience

  • B.Sc., University of Science and Technology of China, Hefei, China (1982)
  • M. Sc., Shanghai Institute of Cell Biology, Chinese Academy of Sciences, China (1985)
  • PhD, University of Cologne, Germany (1991)
  • Research Associate, Shanghai Institute of Cell Biology, Chinese Academy of Sciences, China (1985-1987)
  • Research Fellow, Institute for Genetics, University of Cologne, Germany (1991-1994)
  • Head, Lymphocyte Development Unit, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institute of Health, Maryland, USA (1994-2003)
  • Irene Diamond Associate Professor of Immunology, Chief, Laboratory of Lymphocyte Biology, Department of Microbiology, Columbia University, New York, USA (2003-2011)
Hua Gu
Research Unit Director
Liying Gong
M.Sc. student
Michael Gong
M.Sc. student
Ping Kuang
PhD student
Xin Li
PhD Student
Weili Sun
PhD student
Xiaochen Zhang
PhD student
Mélanie Candido
Administrative Assistant


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Contact information

Montreal Clinical Research Institute (IRCM)
110, des Pins Avenue West
Montréal, Québec  H2W 1R7

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Immunity and Viral Infections