Genetics and Development
The Genetics and Development Research Unit’s primary research interest is to understand the genetics underlying patterning events in the developing embryo. Specifically, the research projects developed in the laboratory focus on the function and regulation of the Hox gene family, whose dysfunctions have been associated with congenital diseases in humans.
The research goal is to identify the mechanisms controlling the regulation of Hox genes and their implication in patterning events as well as morphological evolution among vertebrates. Research projects combine genetics and genomics approaches, and primarily take advantage of the mouse as model system.
- Director, Neurobiology and Development Research Division, IRCM
- Director, Genetics and Development Research Unit, IRCM
- Full IRCM Research Professor
- Associate Research Professor, Department of Medicine (accreditation in molecular biology), Université de Montréal
- Adjunct Professor, Department of Medicine (Division of Experimental Medicine), McGill University
- Holder of the Canada Research Chair in Molecular Embryology and Genetics
- Member, Society for Developmental Biology
Awards and honours
- 2008 Canadian Young Investigator Award in Biological Science, Boehringer Ingelheim Canada
Degrees and relevant experience
- PhD in cell and molecular biology under the joint supervision of Professors Jacques Bierne and Walter Gehring, Université de Reims, France
- Postdoctoral fellowship under the supervision of Professor Walter Gehring, Biozentrum of the University of Basel, Switzerland
- Postdoctoral fellowship under the supervision of Professor Denis Duboule, University of Geneva, Switzerland
- Associate lecturer, Professor Denis Duboule’s laboratory, University of Geneva, Switzerland
Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chédotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. - Cell Reports 2020 Nov 24
Przydacz M, Dudek P, Golabek T, Choragwicki D, Kmita M, Czech AK, Curylo L, Chlosta P, Neurogenic bladder symptom score: Polish translation, adaptation and validation of urinary disorder-specific instrument for patients with neurogenic lower urinary tract dysfunction. - International Journal Of Clinical Practice 2020 Jun 9
ICI Première (Les années lumière) - Marie Kmita answers Sophie-Andrée Blondin's questions about ghost muscles in the human embryo.
Télé-Québec (Électrons libres) - Marie Kmita and her team went back in time and identified the genetic mutation that makes you have 5 fingers.
Québec Science - Marie Kmita and her team discovered how our ancient ancestors ended up with five fingers per hand.
Support biomedical research
Montreal Clinical Research Institute (IRCM)
110, des Pins Avenue West
Montréal, Québec H2W 1R7