Cardiovascular and Metabolic Diseases

Metabolic Diseases

Under the direction of Rémi Rabasa-Lhoret

Research Unit

The Metabolic Diseases Research Unit conducts research projects on diabetes. The different research projects carried out focus on type 1 diabetes and cystic fibrosis related diabetes. Some of our projects also address type 2 diabetes. 

Type 1 diabetes accounts for approximately 10% of all cases and is usually diagnosed during childhood. Type 1 diabetes is generally treated by intensive insulin therapy using multiple daily injections or continuous subcutaneous insulin infusion pump. Despite available treatments, more than 60% of patients with type 1 diabetes do not achieve recommended glycemic (blood sugar) targets. Wide variations in sugar concentrations are observed and can lead to serious complications due to hyperglycemia (high blood sugar: damage to eyes, kidney and nerves) and hypoglycemia (low blood sugar: malaise and loss of consciousness). 

The life expectancy of people with cystic fibrosis improves regularly. New major complications, such as cystic fibrosis related diabetes (high blood glucose levels), have emerged. The causes of cystic fibrosis related diabetes are not well established. The laboratory is attempting to shed light on the mechanisms involved in the development of cystic fibrosis related diabetes as well as on the association between high blood glucose levels and changes in weight and pulmonary function. The team also study various strategies to prevent or delay the development of cystic fibrosis related diabetes and its complications. 

Rémi Rabasa-Lhoret

Research Unit and Clinic Director

  • Director, Metabolic Diseases research unit
  • Director, Diabetes Clinic
  • Director, research platform on obesity, metabolism and diabetes
  • Full IRCM Research Professor
  • Geographical full time associate professor, Department of Nutrition, Faculté de médecine, Université de Montréal
  • Physician, Endocrinology Division, Medicine Department, CHUM
  • Associate researcher, CHUM Research Centre
  • Adjunct Professor, Department of Medicine (Division of Experimental Medicine), McGill University
  • Holder of the J.A. DeSève Chair in clinical research

Awards and honours

  • 2017 Research Award, from the FMSQ (Fédération des médecins spécialistes du Québec)
  • 2015 IMS BROGAN Award, from the FMSQ (Fédération des médecins spécialistes du Québec)
  • Three awards for excellence in teaching (2012, 2013-2014), Université de Montréal
  • 2012 Pierre-Bois Excellence Award, IRCM Foundation
  • 2010 Young Investigator Award, Canadian Society of Endocrinology and Metabolism

Other(s) function(s)

Rémi Rabasa-Lhoret
Research Unit and Clinic Director
Cindy Bergeron
M.Sc. Student
Anne Bonhoure
M.Sc. Student
Valérie Boudreau
PhD Student
Inès Boukabous
Danijela Bovan
Johann Colomba
PhD Student
Katherine Desjardins
Annie Gaumond
Josée Gagnon
Project Coordinator
Lucas Goulet-Gélinas
M.Sc. Student
Catherine Lehoux-Dubois
M.Sc. Student
Catherine Leroux
Virginie Messier
Research Assistant
Diane Mignault
Research Assistant
Élisabeth Nguyen
M.Sc. Student
Khiem Nguyen
Administrative Technician
Valérie Parent
Marie Raffray
Corinne Suppère
Sémah Tagougui
Postdoctoral Fellow
Nadine Taleb
PhD Student
Josée Therrien
Administrative Assistant
May Faraj
Research Unit Director
Mathieu Ferron
Research Unit Director

Projects and major discoveries


Dr. Rabasa-Lhoret actively participates to knowledge dissemination and continuing medical education. He has given more than 300 conferences up to now.

  • J-A De Sève Foundation (research chair managed by IRCM)
  • Canadian Institutes of Health Research (CIHR) 
  • National Institute of Health (NIH, United States) 
  • Juvenile Diabetes Research Foundation (Canada & international) 
  • Diabetes Canada
  • Cystic Fibrosis Canada
  • Cystic Fibrosis Foundation (United States)
  • Société Francophone du Diabète (SFD)
  • Fondation du grand Défi Pierre Lavoie, Corporation de rechercher et d’action sur les maladies héréditaires, Fondation pour la recherche médicale (scholarships for graduate students)


  • Funds from pharmaceuticals companies for research initiated by the industry of y our research group. 
  • Donation from individuals or associations (Diabète Lanaudière, etc.)

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Contact information

Montreal Clinical Research Institute (IRCM)
110, des Pins Avenue West
Montréal, Québec  H2W 1R7

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Cardiovascular and Metabolic Diseases