Cardiovascular and Metabolic Diseases

Molecular Physiology

Under the direction of Mathieu Ferron

Research Unit

Diabetes, obesity and osteoporosis are growing health issues in western countries. The Molecular Physiology Research Unit aims to understand the molecular and physiological mechanisms underlying these metabolic disorders, with the long-term goal of developing novel therapeutic approaches.

The team is also more generally interested in identifying and characterizing new inter-organ relationships implicated in normal physiology or in pathological conditions.

For instance, the current research focus includes characterizing the biological roles of vitamin K in glucose homeostasis and metabolism, in bone health and in coagulation, and understanding the functions of osteocalcin, a recently identified hormone produced by bones that affects energy metabolism.

See the Research Unit Director's list of scientific articles.

Mathieu Ferron

Research Unit Director

  • Director, Cardiovascular and Metabolic Diseases Research Division, IRCM
  • Director, Molecular Physiology Research Unit, IRCM
  • Associate IRCM Research Professor
  • Associate Research Professor, Department of Medicine (accreditation in molecular biology, and in biochemistry and molecular medicine), Université de Montréal
  • Canada Research Chair holder in Bone and Energy Metabolism
  • Adjunct Professor, Department of Medicine, Division of Experimental Medicine, McGill University

Other affiliations

  • Member, Montreal Diabetes Research Center
  • Member, CMDO
  • Member, RSBO

Awards and honours

  • Jean-Davignon/Novo Nordisk Young Investigator Award 2020, Research Network on Cardiometabolic Health, Diabetes and Obesity (CMDO)
  • Étoiles Effervescence Award 2019
  • 2017 Pierre-Bois Excellence Award, IRCM Foundation
  • 2014 Early Investigators Award, Endocrine Society
  • Helmsley Charitable Trust Abstract Award in type 1 diabetes (2014), Endocrine Society
  • The Endocrine Society Outstanding Abstract Award (2013), Endocrine Society
  • K99/R00 Pathway to Independence Award 2012-2013, National Institute of Diabetes and Digestive and Kidney Diseases
  • ASBMR John Haddad Young Investigator Award 2011

Degrees and relevant experience

  • B.Sc., Department of Biochemistry, Université de Montréal (1998)
  • PhD in molecular biology, Department of Medicine, Université de Montréal (2006)
  • Postdoctoral fellowship, Department of Genetics and Development, Columbia University, New York, USA (2006-2011)
  • Research Associate, Department of Genetics and Development, Columbia University, New York, USA (2011-2013)
Mathieu Ferron
Research Unit Director
Julie Lacombe
Research Associate
Kevin Guo
PhD Student
Céline Schott
PhD student
Mariana Correro
Administrative Assistant
Kiani Shayesteh
Doctoral Student
Jean-François Côté
Interim President and Scientific Director of the IRCM; Vice President Research and Academic Affairs; Research Unit Director
May Faraj
Research Unit Director
Rémi Rabasa-Lhoret
Research Unit and Clinic Director
Nabil G. Seidah
Research Unit Director

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Contact information

Molecular Physiology Research Unit
Mathieu Ferron, Director
514 987-5754 |

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Cardiovascular and Metabolic Diseases