Immunity and Viral Infections

Molecular Oncology

Under the direction of André Veillette

Research Unit

The Molecular Oncology Research Unit is interested in signal transduction mechanisms in the immune and hematopoietic systems. Over the past decades, André Veillette's team has identified and characterized numerous cell surface and intracellular molecules that play a crucial role in normal cell physiology.

A number of these molecules are directly or indirectly involved the pathogenesis of leukemias, lymphomas and other malignancies. They have also been linked to the development of certain immunodeficiencies. These proteins are potential targets in therapeutic immunosuppression for the treatment of autoimmune diseases and graft rejection. They can also be targeted to improve immune responses against cancer.

The team uses novel molecular, genomics, mouse genetics and proteomics approaches to study these molecules.

André Veillette

Research Unit Director

  • Director, Molecular Oncology Research Unit, IRCM
  • Full IRCM Research Professor 
  • Full Research Professor, Department of Medicine, Université de Montréal 
  • Adjunct Professor, Department of Medicine (Division of Experimental Medicine), McGill University 
  • Canada Research Chairholder in Immune System Signalling

Awards, honours and other affiliations

  • Fellow, Royal Society of Canada 
  • Member, Association of American Physicians 
  • Member, American Society for Microbiology 
  • Member, American Society for Clinical Investigation 
  • Member, American Association for the Advancement of Science 
  • Member, Canadian Society for Immunology 
  • Member, Society for Natural Immunity 
  • 2009 Bernhard Cinader Award, Canadian Society for Immunology 
  • Recipient, Prix Léo-Parizeau 2007, Association francophone pour le savoir

Degrees and relevant experience

  • MD, Université Laval (1981) 
  • Internship and residency in internal medicine, Montreal General Hospital (1981-1984) 
  • Fellowship in medical oncology, National Cancer Institute (1984-1987) 
  • Postdoctoral fellowship, Medical Breast Cancer Section and Laboratory of Tumor Virus Biology, National Cancer Institute (1985-1989) 
  • Assistant Professor, McGill University (1989-1993) 
  • Associate Professor, McGill University (1993-1999) 
  • Professor, Department of Molecular Oncology, IRCM (since 1999) 
  • Adjunct Professor, Department of Medicine, McGill University (since 1999)
André Veillette
Research Unit Director
Vitalij Cernysiov
Postdoctoral fellow
Jun Chen
Postdoctoral fellow
William Chen
Technical Support
Dominique Davidson
Senior Research Associate
Cristian Camilo Galindo
PhD student
Bin Li
PhD student
Rui Li
PhD student
Yue Ru Li
Technical Support
Yan Lu
Postdoctoral fellow
Vijaya Madhoo
Administrative Assistant
Jin Qian
Research Assistant
Donald Cuong Vinh
Visiting Scientist
Zhaoyu Wang
M.Sc. student
Ning Wu
Research Associate
Ming-Chao Zhong
Research Associate

Major discoveries

Publications

2017

  • Invited speaker: Easton Seminar, University of Toronto, Toronto, Ontario, Canada, November 20, 2017
  • Invited speaker: Landsteiner Lecture Series, Sanquin, Amsterdam, The Netherlands, November 6, 2017
  • Invited speaker: Tongji Hospital Medical Science Summit, Tongji Hospital, Wuhan, China, October 26-27, 2017
  • Invited speaker: Blood Research Institute, Milwaukee, Wisconsin, USA, September 25-26, 2017
  • Invited speaker: Europhosphatase 2017: Phosphatases in cell fates and decisions, Paris, France, July 23-28, 2017
  • Invited speaker: Surface Oncology, Cambridge, Massachusetts, USA, July 13, 2017
  • Invited speaker: FASEB Science Research Conference, Snowmass, Colorado, USA, June 18-23, 2017
  • Keynote speaker: 9th Annual Ontario-Quebec Undergraduate Immunology Conference (OQUIC), Toronto, Ontario, Canada, May 6-7, 2017
  • Invited speaker: 30th Annual Spring Meeting of the Canadian Society for Immunology, Banff, Alberta, Canada, April 7-10, 2017
  • Invited speaker: IDIGH Program Seminar Series, Research Institute of McGill University Health Centre, Montreal, Quebec, Canada, March 22, 2017

2016

  • Invited speaker: 16th Meeting of the Society for Natural Immunity (NK2016), Taormina, Italy, October 2-5, 2016
  • Invited speaker: 16th IUBMB Conference of Biochemistry and Molecular Biology: Signaling Pathways in Development, Disease and Aging, Vancouver, British Columbia, Canada, July 17-21, 2016
  • Invited speaker: Signalisation Québec 2016, Bécancour, Québec, Canada, June 8-10, 2016
  • Invited speaker: Bristol-Myers Squibb, San Francisco, California, USA, April 1, 2016
  • Invited speaker: School of Integrative and Global Majors (SIGMA), University of Tsukuba, Tsukuba, Ibaraki, Japan, February 12, 2016
  • Invited speaker: WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan, February 5, 2016
  • Canadian Institutes of Health Research (Canada-Israel Joint Grant), 2016-2019
  • Bristol-Myers Squibb (Contract), 2016-2019
  • Canadian Institutes of Health Research (Foundation Grant), 2015-2022

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Contact information

Montreal Clinical Research Institute (IRCM)
110, des Pins Avenue West
Montréal, Québec  H2W 1R7

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Immunity and Viral Infections