Participate in a clinical study

Carbohydrates Under Target for Type 1 Diabetes Management (CUT-T1D)

Research project on the very-low-carbohydrate-high-fat diet (ketogenic diet) compared to a control diet (recommended by Diabetes Canada).
The objectives of this project are to evaluate how to adjust insulin and what are the short-term health effects in patients with type 1 diabetes who adopt the ketogenic diet.

The study includes 5 visits at the IRCM spread over 6 months and is divided into 4 phases:

  • Visit 1: Aims to determine eligibility to participate in the study. It included different tests to assess your health. Duration of the visit ≈4h.
    • Start of phase 1: Adjust insulin doses (1 to 3 weeks).
  • Visit 2: Includes teachings to start and follow one of the two diets (ketogenic or control, random order). Duration of the visit ≈1h30.
    • Start of phase 2: Adoption of the 1st diet for 6 weeks.
  • Visit 3: Includes the various tests to assess your health at the end of the diet. Duration of the visit ≈2h30.
    • Start of phase 3: Return to your regular habits for 4 weeks.
  • Visit 4: Includes teachings to begin and follow the second diet (ketogenic or control). Duration of the visit ≈1h30.
    • Start of phase 4: Adoption of the 2nd diet for 6 weeks.
  • Visit 5: Includes the various tests to assess your health at the end of the diet. Duration of the visit ≈2h30.

There will also have 3 visits at the CHUM to have an MRI (Magnetic Resonance Imaging) examination of the liver. The duration of each of these visits is approximately 45 minutes.

The results of this research project will provide healthcare professionals with important information to guide and support patients who choose to adhere to this diet.

This project is under the direction of Dr. Rémi Rabasa-Lhoret, researcher and physician, and Dr. Anne-Sophie Brazeau, researcher and nutritionist.
 

Inclusion criteria

•    Be 18 years old or older;
•    Have been diagnosed with type 1 diabetes for at least 1 year;
•    Use at least 4 insulin injections per day or an insulin pump; 
•    Own a smartphone or tablet.

Informations

Élisabeth Nguyen, RD, M.Sc. student

Elisabeth.nguyen@ircm.qc.ca

514-987-5500 ext. 3238