The IRCM Clinic is seeking pstients with type 1 diabetes to participate in a research project assessing the efficacy of reducing basal insulin to reduce exercise-induced hypoglycemia in adolescents and adults with type 1 diabetes. This study aims to test strategies to reduce the risk of exercise-induced and post-exercise hypoglycemia.
A financial compensation will be given for each intervention completed. The project is being conducted under the supervision of Dr. Laurent Legault (Montreal Children’s Hospital), Dr. Rémi Rabasa-Lhoret (IRCM) and Dr. Mélanie Henderson (Centre hospitalier universitaire Sainte-Justine).
Have type 1 diabetes for at least 2 years
Be over 14 years old
Use insulin pump therapy for more than 3 months
This study involves 3 visits that can be undertaken over 3 months. A first visit to determine your eligibility to participate in the study will take place at the IRCM. The duration of this visit is approximately three hours. Subsequently, two intervention visits to test two strategies to reduce exercise-induced hypoglycemia: reducing basal insulin by 80% 90 minutes before exercise onset, and reducing basal insulin by 80% 40 minutes before exercise onset. Each intervention involves a 3.5 hours stay at the IRCM.
The efficacy of two strategies applied after exercise to reduce the risk of post-exercise hypoglycemia will be assessed with reduced insulin basal rate after exercise and reduced insulin bolus with dinner, and post-exercise snack, regular insulin bolus at dinner and an evening snack.