Reduction of hypoglycemia during continuous exercise and one exercise per interval
The Clinic of the Institut de recherche cliniques de Montréal (IRCM) is seeking participants for a research project on the effectiveness of basal insulin dose reduction in reducing hypoglycemia during continuous exercise and interval exercise in adolescents and adults with type 1 diabetes using the insulin pump. The objective of this study is to test strategies to reduce the risk of hypoglycemia during and after exercise.
Financial compensation will be given. The project is being carried out under the supervision of Dr. Laurent Legault (Montreal Children's Hospital), Dr. Rémi Rabasa-Lhoret (IRCM) and Dr. Melanie Henderson (Centre hospitalier universitaire Sainte-Justine).
This study involves five visits within a period of five months. A first visit is made to the IRCM to determine your eligibility. This visit lasts about three hours. Subsequently, four visits are planned to test two different strategies to reduce hypoglycemia during exercise (continuous or interval): reducing the basal insulin dose by 80% 90 minutes before the start of exercise, and reducing the basal insulin dose by 40% 90 minutes before the start of exercise.
Both strategies will involve two 3.5-hour visits to the IRCM. The effectiveness of two post-exercise strategies to reduce the risk of post-exercise hypoglycemia will be evaluated by reducing the basal insulin dose and reducing the supper bolus, and snacking after exercise, regular bolus at dinner and afternoon snack.
Have been diagnosed with type 1 diabetes for more than two years