Cardiovascular and Metabolic Diseases

Experimental Cardiovascular Biology

Under the direction of Christian F. Deschepper

Research Unit

The Experimental Cardiovascular Biology Research Unit, directed by Christian F. Deschepper, uses several mouse genetic models to better understand the contributions of genetic variants to complex cardiac phenotypes.  

More recently, members of the laboratory have been focusing our efforts on genes carried by the male-specific chromosome Y.  

See the Research Unit Director's list of scientific articles.

Christian F. Deschepper

Research Unit Director

  • Director, Experimental Cardiovascular Biology Research Unit, IRCM
  • Full IRCM Research Professor
  • Full Research Professor, Department of Medicine (accreditation in molecular biology and physiology), Université de Montréal.
  • Adjunct Professor, Department of Medicine (Division of Experimental Medicine), McGill University

Awards and honours

  • Lewis K. Dahl Memorial Lectureship Award (2009), American Heart Association

Degrees and relevant experience

  • MD, Université Libre de Bruxelles, Belgium (1979)
  • Residency in internal medicine, Brussels, Belgium (1979-1982)
  • Postdoctoral fellowship, Department of Physiology, University of California, San Francisco (UCSF), USA (1983-1987)
  • Assistant Research Physiologist, Department of Physiology, UCSF, USA (1987-1990)
  • Adjunct Assistant Professor, Department of Physiology, UCSF, USA (1990-1992)
     
Christian F. Deschepper
Research Unit Director
Mélanie Candido
Administrative Assistant

Major discoveries

Publications

2017

  • April 10, 2017: Invited presentation at the Lady Davis Research Institute. Title: “Genetic and epigenetic regulation of cardiac complex and/or male-specific traits in mouse models”
  • March 10, 2017: Invited presentation at Centre de recherché du CHU de Québec-Université Laval”. Title: “Caractéristiques cardiaques propres au sexe mâle; un dialogue entre les androgènes et le chromosome Y”

2015

  • April 18-21, 2015: Invited presentation at American Society of Andrology; April 18-21, 2015 (Salt Lake City, UT). Title: “Genetic variants of chromosome Y (chrY) regulate the responses of cardiac genes to androgens via chromatin-dependent and circadian related effects”
  • March 29, 2015: Invited presentation in Featured Topic Session at Experimental Biology 2015  (Boston, MA). Title: “Chromosome Y variants: regulatory effects via chromatin modifications and circadian regulation”

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Contact information

Montreal Clinical Research Institute (IRCM)
110, des Pins Avenue West
Montréal, Québec  H2W 1R7

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Cardiovascular and Metabolic Diseases